Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02884-7 Mutations in the gene encoding APP, the precursor to amyloid-β, are found to underpin some cases of familial Alzheimer’s disease.
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02948-8 Genetic evidence kick-starts research into the involvement of microglia cells and the innate immune system in the development of the disease.
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02946-w Immunizing mice against amyloid-β is shown not only to prevent plaques forming, but also to clear away existing deposits.
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02882-9 Evidence mounts that these peptides are the key component of plaques associated with Alzheimer’s and might give rise to the disease.
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02885-6 The APOE gene, which codes for a fat-binding protein in the brain, is identified as a strong genetic risk factor for the...
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02949-7 A study of nearly 75,000 people doubled the number of areas of the human genome that were known to be associated with...
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02883-8 The protein tau is identified as the core component of neurofibrillary tangles — nearly 80 years after the structures were spotted in...
Nature, Published online: 26 September 2024; doi:10.1038/s41586-024-08032-5 Addendum: A graph placement methodology for fast chip design
Nature, Published online: 26 September 2024; doi:10.1038/d41586-024-02901-9 Wetlands ecologist Sigit Sasmito describes how growing up in rural Indonesia influenced his interest in peatlands and mangroves.
Nature, Published online: 26 September 2024; doi:10.1038/s41586-024-07957-1 Author Correction: A molecular and cellular perspective on human brain evolution and tempo
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