16
Oct

Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Nature, Published online: 16 October 2024; doi:10.1038/s41586-024-08061-0

Cell-type-resolved spatial proteomics of the skin from patients with toxic epidermal necrolysis reveals that it is driven by JAK/STAT signaling, leading to successful treatment of this potentially fatal condition in patients using JAK inhibitors.